News

Dr. Shieh has been appointed as an associate editor of 'STAT' , which will be lauched in Aug, 2012.

Congratulations to our team members whose paper: "Inferring Genetic Interactions via A Data-driven Second Order Model," published by the Frontiers in Statistical Genetics and Methodology (2012).

Congratulations to our team members whose paper: "H2B ubiquitylation is part of chromatin architecture that marks exon-intron structure in budding yeast," published by the BMC Genomics (2011).

Congratulations to our team members whose paper: "Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model," published by the Carcinogenesis (2011).

Dr. Shieh has been appointed as an associate editor of 'Frontiers in Statistical Genetics and Methodology' ! (The journal website)

Congratulations to our team members whose paper: "Modeling and Comparing the Organization of Circular Genomes," published by the Bioinformatics (2011).

1. Analyzing (a) Epigenetics, methylation binding domain (MBD)capture sequencing, (b) Microarray gene expression data and (c) microRNAs to uncover genes and pathways involved in ovarian cancer / endometrial cancer. (collaborate with Prof. Hung-Cheng Lai (National Defense Medical Center).)
   
   
2. Analyzing microarray gene expression data to infer partial pathways involved in breast cancer stem cell (BCSC). (collaborate with Prof. Alice Chen (GRC, Academia Sinica).)
   
   
3. Using genetic interactions to develop novel cancer therapeutic agents. (collaborate with Prof. Jan-Gowth Chang(Kaoshung Medical Univ.), Dr. Konan Peck(IBMS, Academia Sinica), Jeou-Yuan Chen(IBMS, Academia Sinica).)
   
   
4. Analyzing microarray gene expression data to infer partial pathways involved in (a) carcinogenesis of Hepatocellular carcinoma in mouse. (b) obesity in human.
   (a) collaborate with Dr. C. H. Cathy Yuh at NHRI
   (b) collaborate with Drs. J. D. Zucker and Karine Clement, IRD and INSERM, FRANCE.
   
   
5. Analyzing genomic data, Epigenetic (ChIP-chip, ChIP-sequencing) and gene expression data, to find novel biological phenomenon, e.g. chromatin remodeling in S. cerevisiae. (collaborate with Dr. Chen-Fu Kao at IOCB, Academia Sinica)
   
   
6. Using several kinds of genomic data to infer genetic interactions / pathway components.