|
|
|
楊欣洲
Hsin-Chou
Yang
Institute
of Statistical Science Academia Sinica
Taipei 11529, Taiwan, R.O.C.
Tel: 886-2-27835611 ext. 113
FAX : 886-2-27831523
E-mail: hsinchou@stat.sinica.edu.tw
|
|
Research Interests (PDF file)
|
|
1.
Genetic/Genomic statistics - Identify disease susceptibility genes
by using genetic marker data
2. Ecological
statistics - Study population abundance by using capture recapture data
|
Education
|
|
1990 - 1994
|
B.S., Department of Statistics, National Cheng Kung
University.
|
|
|
1994 - 1996
|
M.S., Graduate Institute
of Statistics, National Cheng
Kung University.
|
|
|
1996 - 2002
|
Ph.D., Institute of Statistics, National Tsing
Hua University.
|
Professional
Experience
|
|
2002.10 - 2004.06
|
Institute of Biomedical Sciences, Academia Sinica (Postdoctoral Fellow of National
Science Council) [In military service]
|
|
|
2004.07 - 2006.06
|
Institute of Biomedical Sciences, Academia Sinica (Postdoctoral Fellow of Academia
Sinica) [In military service]
|
|
|
2006.07 - Present
|
Institute of Statistical Science, Academia
Sinica (Assistant Research Fellow)
|
Publications
|
- Journal
Papers
|
1.
|
|
Huggins,
R. M., Yang, H.-C., Chao, A. and Yip,
P. S. F. (2003). Population size estimation using local sample coverage for
open populations. Journal of Statistical Planning and
Inference 113, 699-714. [SCI]
|
|
2.
|
|
Yang, H.-C. and Huggins, R. M. (2003). The estimation of the size of
an open population using local estimating equations. Statistica
Sinica 13, 673-689. [SCI]
|
|
3.
|
|
Yang, H.-C., Huggins, R. M.
and Clark, A. (2003). Estimation of the size of an open population using
local estimating equations II: A semi-parametric approach. Biometrics 59,
365-374. [SCI]
|
|
4.
|
|
Lin, Y. M. J., Yang,
H.-C., Lai, T. J., Fann, C. S. J. and Sun, H. S. (2003).
Receptor mediated effect of serotonergic
transmission in patients with bipolar affective disorder. Journal
of Medical Genetics 40, 781-786. [SCI]
|
|
5.
|
|
Lo, Y.-L., Yu, J.-C.,
Chen, S.-T., Yang, H.-C., Fann, C. S. J., Mau, Y.-C. and Shen, C.-Y. (2005). Breast
cancer risk associated with genotypic polymorphism of the
mitosis-regulating gene, Aurora-A/STK15/BTAK. International
Journal of Cancer 115, 276-283. [SCI]
|
|
6.
|
|
Yang, H.-C., Pan C.-C., Lu,
R. C. Y. and Fann, C. S. J. (2005). New adjustment factors and sample size
calculation in a DNA-pooling experiment with preferential amplification. Genetics 169,
399-410. [SCI]
|
|
7.
|
|
Yang, H.-C., Chambers, L. and
Huggins, R. M. (2005). A seasonal decomposition of the estimated size of a
penguin population at Phillip Island, Australia. Australian
Journal of Zoology 53, 111-115. [SCI]
|
|
8.
|
|
Yang, H.-C. and Chao, A. (2005). Modeling animals’ behavioral
response by Markov chain models for capture-recapture experiments. Biometrics 61,
1010-1017. [SCI]
|
|
9.
|
|
Yang, H.-C., Chang, C.-C.,
Lin, C.-Y., Chen, C.-L., Lin, C.-Y. and Fann, C.
S. J. (2005). A genome-wide scanning and fine mapping study of COGA data. BMC
Genetics 6, S30. [SCI]
|
|
10.
|
|
Yang, H.-C., Lin, C.-H.,
Hung, S.-I. and Fann, C. S. J. (2006). A
comparison of individual genotyping and pooled DNA analysis for polymorphism
validation prior to large-scale genetic studies. Annals of
Human Genetics 70, 350-359. [SCI]
|
|
11.
|
|
Yang, H.-C., Pan, C.-C., Lin,
C.-Y. and Fann, C. S. J. (2006). PDA: Pooled DNA
analyzer. BMC Bioinformatics 7, 233.
[SCI]
|
|
12.
|
|
Yang, H.-C., Lin, C.-H., Hsu, C.-L., Hung, S.-I., Wu, J.-Y., Pan, W.-H., Chen,
Y.-T. and Fann, C. S. J. (2006). A
comparison of major histocompatibility complex SNPs in Han Chinese residing
in Taiwan and
Caucasians. Journal of Biomedical Science 13,
489-498. [SCI]
|
|
13.
|
|
Yang, H.-C., Lin, C.-Y. and Fann, C. S. J. (2006). A sliding-window weighted
linkage disequilibrium test. Genetic Epidemiology 30,
531-545. [SCI]
|
|
14.
|
|
Yang, H.-C., Liang, Y.-J., Huang, M.-C., Li, L.-H., Lin, C.-H., Wu, J.-Y., Chen, Y.-T. and Fann, C. S. J. (2006). A
genome-wide study of preferential amplification/hybridization in
microarray-based pooled DNA experiments. Nucleic Acids
Research 34, e106. [SCI]
|
|
15.
|
|
Yang, H.-C., Huang,
M.-C., Li, L.-H., Lin, C.-H., Yu, L. T., Diccianni,
M. B., Wu, J.-Y., Chen, Y.-T. and Fann, C. S. J.
(2008). MPDA: microarray-based pooled DNA analyzer. BMC Bioinformatics 9, 196. [SCI]
|
|
16.
|
|
Yang, H.-C., Hsieh,
H.-Y. and Fann, C. S. J. (2008). KBAT:
Kernel-based association test. Genetics 179, 1057-1068. [SCI]
|
|
17.
|
|
Wang, R.-Y., Chung, C.-M., Fann, C.S.J., Yang, H.-C., Chen, J.-W., Jong, Y.-S., Jou, Y.-S., Lo, H.-M., Ho, F.-M., Kang, C.-S., Chen, C.-C., Chang, H.-C., Shyue, S.-K. and Pan,
W.-H. (2008). Genome-wide
scan for quantitative ACE activity in Taiwan young-onset hypertension
study. Human Heredity 65, 85-90. [SCI]
|
|
18.
|
|
Zhang, H., Yang, H.-C.
and Yang Y. (2008). PoooL: An efficient algorithm
for estimating haplotypes from large DNA pools. Bioinformatics, Advance Access
published online on June 23, 2008. [SCI]
|
- Book Chapters
|
1.
|
|
Chao, A., Yang, H.-C. and
Yip, P. S. F. (2003). The use of capture-recapture methodology in
epidemiological surveillance. In Advanced Medical Statistics ,
published by The World Scientific Publishing Company, Singapore.
|
|
2.
|
|
Yang, H.-C. and Fann, C. S. J. (2007). Association mapping using
pooled DNA. In Linkage Disequilibrium and Association
Mapping, published by The Humana Press Inc., USA.
|
-
Software and Database
|
1.
|
|
CARE-2
(Capture-Recapture Part 2)
Authors:
Chao, A. and Yang, H.-C.
Website:
http://chao.stat.nthu.edu.tw/softwareCE.html
|
|
2.
|
|
CARE-4
(Capture-Recapture Part 4)
Authors:
Yang, H.-C. and Chao,
A.
Website: http://chao.stat.nthu.edu.tw/softwareCE.html
|
|
3.
|
|
Database
of CPA (Coefficient of Preferential Amplification/Hybridization)
Authors: Yang, H.-C.,
Liang, Y.-J., Huang, M.-C., Li, L.-H., Lin, C.-H., Wu, J.-Y., Chen, Y.-T. and Fann, C. S. J.
Website: http://www.ibms.sinica.edu.tw/~csjfann/first
flow/database.htm
|
|
4.
|
|
PDA
(Pooled DNA Analyzer)
Authors:
Yang, H.-C., Pan, C.-C., Lin, C.-Y. and Fann, C. S. J.
Website:
http://www.ibms.sinica.edu.tw/~csjfann/first flow/pda.htm
|
|
5.
|
|
KBAT (Kernel-Based Association Test)
Authors: Yang, H.-C.,
Hsieh, H.-Y. and Fann, C. S. J.
|
|
6.
|
|
MPDA (Microarray Pooled DNA Analyzer)
Authors: Yang, H.-C., Huang,
M.-C., Li, L.-H., Lin, C.-H., Yu, A. L. T., Diccianni,
M. B., Wu, J.-Y., Chen, Y.-T. and Fann,
C. S. J.
|
Others
|
