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楊欣洲
Hsin-Chou
Yang
Institute
of Statistical Science Academia Sinica
Taipei 11529, Taiwan, R.O.C.
Tel: 886-2-27835611 ext. 113
FAX : 886-2-27831523
E-mail: hsinchou@stat.sinica.edu.tw
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Research Interests (PDF file)
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1.
Genetic/Genomic statistics - Identify disease susceptibility genes
by using genetic marker data
2. Ecological
statistics - Study population abundance by using capture recapture data
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Education
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1990 - 1994
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B.S., Department of Statistics, National Cheng Kung
University.
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1994 - 1996
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M.S., Graduate Institute
of Statistics, National Cheng
Kung University.
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1996 - 2002
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Ph.D., Institute of Statistics, National Tsing
Hua University.
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Professional
Experience
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2002.10 - 2004.06
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Institute of Biomedical Sciences, Academia Sinica (Postdoctoral Fellow of National
Science Council) [In military service]
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2004.07 - 2006.06
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Institute of Biomedical Sciences, Academia Sinica (Postdoctoral Fellow of Academia
Sinica) [In military service]
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2006.07 - Present
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Institute of Statistical Science, Academia
Sinica (Assistant Research Fellow)
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Publications
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- Journal
Papers
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1.
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Huggins, R. M., Yang,
H.-C., Chao, A. and Yip, P. S. F. (2003). Population size
estimation using local sample coverage for open populations. Journal
of Statistical Planning and Inference 113,
699-714. [SCI]
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2.
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Yang, H.-C. and Huggins, R. M. (2003). The estimation of the size of
an open population using local estimating equations. Statistica
Sinica 13, 673-689. [SCI]
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3.
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Yang,
H.-C., Huggins, R. M. and Clark, A. (2003). Estimation of
the size of an open population using local estimating equations II: A
semi-parametric approach. Biometrics 59,
365-374. [SCI]
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4.
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Lin, Y. M. J.,
Yang, H.-C., Lai, T. J., Fann, C. S. J. and
Sun, H. S. (2003). Receptor mediated effect of serotonergic
transmission in patients with bipolar affective disorder. Journal
of Medical Genetics 40, 781-786. [SCI]
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5.
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Lo, Y.-L., Yu, J.-C., Chen, S.-T., Yang, H.-C., Fann, C. S. J.,
Mau, Y.-C. and Shen, C.-Y. (2005). Breast cancer risk
associated with genotypic polymorphism of the mitosis-regulating gene,
Aurora-A/STK15/BTAK. International Journal of Cancer 115,
276-283. [SCI]
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6.
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Yang,
H.-C., Pan C.-C., Lu, R. C. Y. and Fann, C. S. J. (2005).
New adjustment factors and sample size calculation in a DNA-pooling
experiment with preferential amplification. Genetics 169,
399-410. [SCI]
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7.
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Yang,
H.-C., Chambers, L. and Huggins, R. M. (2005). A seasonal
decomposition of the estimated size of a penguin population at Phillip
Island, Australia. Australian Journal of Zoology 53,
111-115. [SCI]
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8.
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Yang,
H.-C. and Chao, A. (2005)CA. Modeling animals’ behavioral response by
Markov chain models for capture-recapture experiments. Biometrics 61,
1010-1017. [SCI]
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9.
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Yang,
H.-C., Chang, C.-C., Lin, C.-Y., Chen, C.-L., Lin, C.-Y. and Fann, C. S. J. (2005). A genome-wide scanning and
fine mapping study of COGA data. BMC Genetics 6,
S30. [SCI]
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10.
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Yang,
H.-C., Lin, C.-H., Hung, S.-I. and
Fann, C. S. J. (2006). A comparison of individual genotyping and pooled DNA
analysis for polymorphism validation prior to large-scale genetic studies. Annals of
Human Genetics 70, 350-359. [SCI]
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11.
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Yang,
H.-C., Pan, C.-C., Lin, C.-Y. and
Fann, C. S. J. (2006). PDA: Pooled DNA analyzer. BMC
Bioinformatics 7, 233. [SCI]
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12.
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Yang, H.-C., Lin, C.-H., Hsu,
C.-L., Hung, S.-I., Wu, J.-Y., Pan, W.-H., Chen, Y.-T. and Fann, C. S. J.
(2006). A comparison of major histocompatibility
complex SNPs in Han Chinese residing in Taiwan and
Caucasians. Journal of Biomedical Science 13,
489-498. [SCI]
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13.
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Yang,
H.-C., Lin, C.-Y. and Fann, C. S.
J. (2006). A sliding-window weighted linkage disequilibrium test. Genetic
Epidemiology 30, 531-545. [SCI]
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14.
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Yang, H.-C., Liang, Y.-J.,
Huang, M.-C., Li, L.-H., Lin, C.-H., Wu, J.-Y., Chen, Y.-T. and Fann, C. S. J. (2006). A
genome-wide study of preferential amplification/hybridization in
microarray-based pooled DNA experiments. Nucleic Acids
Research 34, e106. [SCI]
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15.
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Yang, H.-C., Huang, M.-C., Li, L.-H., Lin, C.-H., Yu, L. T., Diccianni, M. B., Wu, J.-Y., Chen, Y.-T. and Fann, C. S. J. (2008)CA.
MPDA: microarray-based pooled DNA analyzer. BMC Bioinformatics 9, 196. [SCI]
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16.
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Yang, H.-C., Hsieh, H.-Y. and Fann, C. S. J. (2008)CA. KBAT: Kernel-based association test.
Genetics
179, 1057-1068. [SCI]
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17.
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Wang, R.-Y., Chung, C.-M., Fann, C.S.J., Yang, H.-C., Chen, J.-W., Jong, Y.-S., Jou, Y.-S., Lo, H.-M., Ho, F.-M., Kang, C.-S., Chen, C.-C., Chang, H.-C., Shyue, S.-K. and Pan,
W.-H. (2008). Genome-wide
scan for quantitative ACE activity in Taiwan young-onset hypertension
study. Human Heredity 65, 85-90. [SCI]
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18.
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Zhang, H., Yang, H.-C. and
Yang Y. (2008). PoooL: An efficient algorithm for estimating haplotypes
from large DNA pools. Bioinformatics 24, 1942-1948. [SCI]
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19.
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Huggins, R., Li, L.-H., Lin, Y.-C., Yu, A.L.T. and Yang, H.-C.
(2008)CA. Nonparametric
estimation of LOH using Affymetrix SNP genotyping arrays for unpaired
samples. Journal
of Human Genetics 53,
983-990. [SCI]
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- Book Chapters
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1.
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Chao,
A., Yang, H.-C. and Yip, P. S. F. (2003). The use
of capture-recapture methodology in epidemiological surveillance. In Advanced
Medical Statistics ,
published by The World Scientific Publishing Company, Singapore.
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2.
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Yang,
H.-C. and Fann, C. S. J. (2007).
Association mapping using pooled DNA. In Linkage
Disequilibrium and Association Mapping, published by The
Humana Press Inc., USA.
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Software and Database
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1.
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CARE-2
(Capture-Recapture Part 2)
Authors:
Chao, A. and Yang, H.-C.
Website:
http://chao.stat.nthu.edu.tw/softwareCE.html
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2.
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CARE-4
(Capture-Recapture Part 4)
Authors:
Yang, H.-C. and Chao,
A.
Website: http://chao.stat.nthu.edu.tw/softwareCE.html
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3.
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Database
of CPA (Coefficient of Preferential Amplification/Hybridization)
Authors:
Yang, H.-C., Liang, Y.-J., Huang, M.-C., Li,
L.-H., Lin, C.-H., Wu, J.-Y., Chen, Y.-T. and
Fann, C. S. J.
Website: http://www.ibms.sinica.edu.tw/~csjfann/first
flow/database.htm
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4.
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PDA
(Pooled DNA Analyzer)
Authors:
Yang, H.-C., Pan, C.-C., Lin, C.-Y. and Fann, C. S. J.
Website:
http://www.csjfann.ibms.sinica.edu.tw/EAG/Program/PDA/Pda.php
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5.
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KBAT (Kernel-Based
Association Test)
Authors: Yang, H.-C., Hsieh, H.-Y. and Fann, C. S. J.
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6.
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MPDA (Microarray
Pooled DNA Analyzer)
Authors: Yang, H.-C., Huang, M.-C., Li,
L.-H., Lin, C.-H., Yu, A. L. T., Diccianni,
M. B., Wu, J.-Y., Chen, Y.-T. and Fann,
C. S. J.
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Others
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