Chen-Hung Kao
Institute of Statistical Science
Academia Sinica
Taipei 11529,
Taiwan, R.O.C.
 Office: (02) 27835611 ext 418
FAX : (02) 2783-1523
E-mail:
chkao@stat.sinica.edu.tw

Fortran-77 MIM Program for Download

gr02632

R Selective Genotyping Program for Download

R program for determining the threshold value using score-statistic approach

R program for QTL hotspot detection

MOST

YEAST


I am interested in developing and utilizing statistical methodology for solving Problems arising in Population and Quantitative Genetics.

EDUCATION

  • Ph.D. in Statistics, North Carolina State University, Raleigh, North Carolina, USA. Degree awarded Aug. 1995.
  • Master of Agronomy, Experimental Statistics, National Taiwan University, Taipei, Taiwan. Degree awarded June, 1990.
  • Bachelor of Science, Agronomy, National Chung-Hsing University, Taichung, Taiwan. Degree awarded June, 1986.

PROFESSIONAL EMPLOYMENT

  • Post-Doctoral Research Associate, Program in Statistical Genetics, Department of Statistics, North Carolina State University, North Carolina, USA, Aug 1995 - Dec 1996.
  • Research Scientist, ForBio Research, Brisbane, Australia, Jan. 1997 - Aug. 1997.
  • Assistant Professor, Department of Finance, Chaoyang University of Technology, Wufeng, Taichung, Taiwan, R.O.C., Sep. 1997 - Aug. 1998.
  • Assistant Research Fellow, Institute of Statistical Science, Academia Sinica, Taipei, Taiwan, R.O.C., Aug. 1998 - July. 2002.
  • Assistant Professor, Department of Biology, National Taiwan Normal University, Taipei, Taiwan, R.O.C., Aug. 1999 - July. 2002.
  • Associate Research Fellow, Institute of Statistical Science, Academia Sinica, Taipei, Taiwan, R.O.C., July. 2002 - present.
  • Adjunct Associate Professor, Department of Agronomy, National Taiwan University, Taipei, Taiwan, R.O.C., Aug. 2006 - present.
  • Research Fellow, Institute of Statistical Science, Academia Sinica, Taipei, Taiwan, R.O.C., May 2011 - present.
  • Adjunct Professor, Department of Agronomy, National Taiwan University, Taipei, Taiwan, R.O.C., Aug. 2011 - present.

SERVICE

  • Organizer of Workshop "Modern Statistical Methods For Gene Mapping In Human and Experimental Populations". September 29-30, 2000, Taipei.
  • Local committee chair of “The 2007 Taipei International Statistical Symposium and ICSA International Conference”. June 25-27, 2007, Taipei
  • Organizer of “2015 Taipei Summer Institute in Statistical Genetics”. Aug. 24-Sep. 4, 2015, Taipei.

SELECTED PUBLICATIONS

  1. KAO, C.-H. and Z.-B. ZENG 1997 General formulas for obtaining the maximum likelihood estimates and the asymptotic variance-covariance matrix in QTL mapping when using the EM algorithm. Biometrics 53, 653-665.
  2. KAO, C.-H., Z.-B. ZENG and R. D. TEASDALE 1999 Multiple interval mapping for Quantitative Trait Loci. Genetics 152: 1203-1216.
  3. ZENG, Z.-B., C.-H. KAO and C. J. BASTEN 1999 Estimating the genetic architecture of quantitative traits. Genetics Research 74: 279-289.
  4. KAO, C.-H. 2000 On the differences between the maximum likelihood and regression interval mapping in the analysis of quantitative trait loci. Genetics 156: 855-865.
  5. KAO, C.-H. and Z.-B. Zeng 2002 Modeling epistasis of quantitative trail loci using Cockerham’s model. Genetics 160: 1243-1261.
  6. KAO, C.-H. 2004 Multiple interval mapping for quantitative trait loci controlling endosperm traits. Genetics 167: 1987-2002.
  7. KAO, C.-H. 2006 Mapping Quantitative Trait Loci Using the Experimental Designs of Recombinant Inbred Population. Genetics 174: 1373-1386.
  8. KAO, C.-H. and M.-H. Zeng 2009 A study on the Mapping Quantitative Trait Loci in Advanced Populations Derived from Two Inbred Lines. Genetics Research 91: 85-99. supplemental material; program.
  9. KAO, C.-H. and M.-H. Zeng 2010 An investigation of the power for separating closely linked QTL in experimental populations. Genetics Research 92: 283-294. supplemental material.
  10. KAO, C.-H. and H.-A. Ho 2012 A score-statistic approach for determining threshold values in QTL mapping. Frontiers in Bioscience. E4, 2670-2682.
  11. H.-I LEE, H.-A. HO and C.-H. KAO 2014 A new simple method for improving QTL mapping under selective genotyping. Genetics 198: 1685-1698.
  12. M.-H. Yang, D.-H. Wu and C.-H. KAO 2019 A Statistical Procedure for Genome-Wide Detection of QTL Hotspots Using Public Databases with Application to Rice. G3: Genes, Genomes, Genetics 9: 439-452.
  13. Wu, P.-Y., M.-.H. Yang, and C.-H. KAO 2021 A Statistical Framework for QTL Hotspot Detection. G3: Genes, Genomes, Genetics: jkab056.