Harnessing Omics Data to Dissect Complex Traits, Drug Responses, and Population Ancestry

Abstract

With rapid advances in high-throughput and high-dimensional molecular profiling in recent years, a wealth of omics data becomes available. Harnessing omics data presents unmet opportunities to decipher the mechanisms of complex diseases, drug responses, and population ancestry. In this talk, I will present our recent accomplishments in developing biostatistical and bioinformatics methodologies and analysis tools for analyzing genomics, transcriptomics, epigenomics, and metabolomics data. I will also present our biological findings in studying population genomics and pharmacogenomics/pharmacoepigenomics.